首页> 外文OA文献 >Prognostic factors in lumbar spinal stenosis surgery. A prospective study of imaging- and patient-related factors in 109 patients who were operated on by decompression
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Prognostic factors in lumbar spinal stenosis surgery. A prospective study of imaging- and patient-related factors in 109 patients who were operated on by decompression

机译:腰椎管狭窄症手术的预后因素。一项前瞻性研究,对109名通过减压手术的患者的影像学和患者相关因素进行了研究

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摘要

Background and purpose A considerable number of patients who undergo surgery for spinal stenosis have residual symptoms and inferior function and health-related quality of life after surgery. There have been few studies on factors that may predict outcome. We tried to find predictors of outcome in surgery for spinal stenosis using patient- and imaging-related factors. Patients and methods 109 patients in the Swedish Spine Register with central spinal stenosis that were operated on by decompression without fusion were prospectively followed up 1 year after surgery. Clinical outcome scores included the EQ-5D, the Oswestry disability index, self-estimated walking distance, and leg and back pain levels (VAS). Central dural sac area, number of levels with stenosis, and spondylolisthesis were included in the MRI analysis. Multivariable analyses were performed to search for correlation between patient-related and imaging factors and clinical outcome at 1-year follow-up. Results Several factors predicted outcome statistically significantly. Duration of leg pain exceeding 2 years predicted inferior outcome in terms of leg and back pain, function, and HRLQoL. Regular and intermittent preoperative users of analgesics had higher levels of back pain at follow-up than those not using analgesics. Low preoperative function predicted low function and dissatisfaction at follow-up. Low preoperative EQ-5D scores predicted a high degree of leg and back pain. Narrow dural sac area predicted more gains in terms of back pain at follow-up and lower absolute leg pain. Interpretation Multiple factors predict outcome in spinal stenosis surgery, most importantly duration of symptoms and preoperative function. Some of these are modifiable and can be targeted. Our findings can be used in the preoperative patient information and aid the surgeon and the patient in a shared decision making process.
机译:背景和目的接受椎管狭窄手术的患者中,有相当多的患者在手术后残留症状,功能低下以及与健康相关的生活质量。关于可能预测结果的因素的研究很少。我们试图使用患者和影像学相关因素寻找脊柱狭窄手术结局的预测指标。患者和方法瑞典脊柱注册中心有109例中枢椎管狭窄的患者,在不合并融合的情况下进行减压手术,预期在术后1年进行随访。临床结果评分包括EQ-5D,Oswestry残疾指数,自我估计的步行距离以及腿部和背部疼痛程度(VAS)。 MRI分析包括硬膜囊中央区域,狭窄程度和脊椎滑脱的数量。进行了多变量分析,以寻找患者相关和影像学因素与1年随访时的临床结局之间的相关性。结果几个因素在统计学上预测结果。腿部疼痛持续时间超过2年,就腿部和背部疼痛,功能和HRLQoL而言,预后较差。术前定期和间歇使用镇痛药的人比不使用镇痛药的人在术后随访时有更高的背痛水平。术前功能低预示着功能低下,随访时不满意。术前EQ-5D得分低预示着腿和背痛的严重程度。狭窄的硬膜囊区域预示着在随访时的背痛和绝对的下肢疼痛会增加。解释多种因素可预测椎管狭窄手术的结果,最重要的是症状持续时间和术前功能。其中一些是可修改的,可以作为目标。我们的发现可用于术前患者信息中,并在共同的决策过程中帮助外科医生和患者。

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